Lipoedema Treatment: Bloodless, No Risk of Fat Embolism, Lymph Protective Superdry 4D

By Prof. Dr Ahmet Karacalar

What is Lipoedema?

Popularly known as ‘Painful Cellulite‘ or ‘Leg Obesity’Lipoedema is a chronic fat metabolism disease that does not respond to diet and sports. It is usually characterised by disproportionate fat accumulation in the hips, thighs and legs.  Lipoedema treatment With its protocols, this condition should be treated not only as an aesthetic problem but also as a metabolic syndrome. In fact, the word lipoedema does not fully describe the disease. It is a syndrome that affects not only adipose tissue but also vessels, sensory nerves, lymph and connective tissue and has systemic effects, especially thyroid.

Prof. Dr Ahmet Karacalar; He describes this condition not only as an aesthetic defect, but also as a metabolic and hormonal syndrome.  Superdry4D (Bloodless, no risk of fat embolism) Technique, It stands out as a very safe surgical approach that removes painful fat from the body without damaging the lymphatic system.

What are the Symptoms of Lipoedema?

If you are experiencing the following symptoms, you should seek a specialist assessment immediately. Especially the following symptoms allow us to make the diagnosis:

  • Disproportionate Size: The upper body is thin, whereas the lower body (hips and legs) remains noticeably thicker.
  • Resistant Lubrication: No matter how much you diet and exercise, unfortunately thick legs it doesn't get thinner.
  • Pain and Sensitivity: You feel a stinging sensation when you touch the legs or experience severe pain at the end of the day.
  • Easy Bruising: Unexplained bruises occur on the legs even with the slightest impact.
  • Stemmer Mark: If the skin of the toes can be held with a clamp, this is in favour of the disease. Otherwise (if it cannot be held), we consider it as lymphoedema.
  • These are the main complaints. In most patients, numbness in the legs, restless legs, coldness or on the contrary burning in the feet, intestinal problems, low energy, thyroid problems are also accompanied.

Lipoedema Types (Distribution Regions)

We classify the disease into 5 different types according to the areas of the body affected. Therefore, we need to determine the type for correct treatment planning:

Type 1: Hips and Buttocks

Fat accumulation is only in the pelvis, hips and thighs. The skin surface is usually smooth, but there is a disproportion between the upper and lower body.

Tip 2: Dize Kadar İnen

Fatty deposits start at the buttocks and go down to the knees. In addition, fat deposits (pads) form on the inside of the knees, which can cause the legs to rub against each other when walking.

Type 3: Up to Ankle (Trouser Type)

It is the most common form. There is thickening from the hip to the ankle. A knot called “Lipoedema Cuff” (Cuff Sign) is formed in the ankle; but we do not see swelling in the feet.

Type 4: Involvement of the Arms

The disease affects not only the legs but also the arms. The diseased arm is usually associated with type 2 or type 3. We observe thickening and sagging up to the wrists.

Type 5: Lower leg only (below the knee)

It's much rarer. We only detect fat deposits between the knee and ankle.

Image of a female leg showing the appearance of lipoedema, symmetrical fat accumulation, tenderness and bruising in the legs

Symmetrical fat and tenderness in the legs with lipoedema

Lipödem Evreleri

This disease has a progressive character. If we do not intervene in time, you will experience a transition between stages:

  • Phase 1 (Inception): The skin surface is still smooth, but the subcutaneous fatty tissue has increased. You will notice increasing swelling during the day.
  • Phase 2 (Progress): Fluctuations on the skin surface become more pronounced, the appearance of “orange peel” increases. Hard fat nodules the size of a walnut appear under the skin.
  • Stage 3 (Advanced Stage): Large fat masses and sagging occur in the legs. You may develop walking difficulties and frictional sores.
  • Stage 4 (Lipo-Lymphedema): The disease is no longer just a problem of adipose tissue; the lymphatic vessels are also impaired. As a result, the picture is accompanied by lymphoedema.
    Medical image showing lipoedema treatment, liposuction and supportive methods varying according to the stages.

    Informative visual explaining the appearance of lipoedema at different stages.

Lipödem teşhisi nasıl konur ?

Lipödem teşhisinde hastanın ağrı, ödem, çabuk morarma şikayetleri yanında ayaklarda soğukluk bazen yanma şikayetleri yanında iki taraflı ancak ayak parmaklarını tutmayan yağlanma şeklinde teşhis kolaydır. Muayenede bazı testler uygulanır. Örneğin Stemmer testi. Aile öyküsü çoğu zaman vardır. Ultrason, sintigrafi ya da MR gibi tanı yöntemleri eklenebilir. Ancak bunlar çoğu zaman gerekli değildir. Ek sorunları araştırmak için değerli olabilir.

Lipödem teşhisi için klinik muayene bulguları, evreleme, diferansiyel tanı ve ilave değerlendirme yöntemlerini gösteren infografik

Lipödem teşhisi: Klinik bulgular, evreleme ve ayırıcı tanı kriterleri

Lipoedema Treatment: Superdry 4D liposuction (bloodless, no embolism risk, lymph protective) 

For permanent treatment of the disease, it is necessary to surgically remove the diseased fat tissue from the body. The advantages of the Superdry 4D Technique developed by Prof. Dr. Ahmet Karacalar and published in international refereed journals and presented at congresses (Singapore and Thailand) are as follows.

  • No bleeding: Thanks to the special tourniquet system, we work in a bloodless environment.
  • Lymph Protector: With the longitudinal technique and thin flexible cannulas, the lymph vessels are not damaged, on the contrary, the lymphatic system relaxes as the fat load is removed.
  • Secure Borders: Since bloodless fat is removed, we remove the maximum safe amount of fat in a single session.
  • Instant Result: Since there is no swelling (oedema) during the procedure, we see the result instantly and it is possible to shape the leg aesthetically.
  • There is no risk of fat embolism.
Important Note:  “It should not be confused with ”dry liposuction". Dry liposuction is a bloody method.   

Other Methods (Laser, Ultrasonic, PAL, Waterjet)

  • Laser Lipolysis It uses heat energy. Therefore, there is a risk of heat damage and discolouration of the thin leg skin.
  • Ultrasonics: There is a risk of heat damage. There is a risk of nerve damage by affecting the fat in the nerve sheaths. There is also a risk of tissue burns.
  • PAL and water jet techniques have a higher safety limit.  

Frequently Asked Questions

Does lipoedema go away without surgery?

No, it's not obesity. It's not obesity, so it doesn't respond to diet and exercise. We need to surgically remove the diseased fat tissue. Non-surgical methods only relieve symptoms, not cure.

How to do lipoedema diet?

This diet is not a standard weight loss diet. On the contrary, our aim here is not to count calories, but to reduce inflation (inflammation) in the body. This tissue is ‘starvation resistant’, but with the right nutrition we can control pain and oedema.

What should a lipoedema patient not eat?

First of all, we recommend an anti-inflammatory (inflammation-reducing) diet. Especially in the pre-menopausal period, you should avoid foods containing phytoestrogens, processed sugar and gluten as much as possible.

Are walking and sports good for you?

Sport improves circulation, but does not dissolve diseased fat. We usually recommend horizontal sports such as swimming. However knee joint You should avoid heavy sports that impose a load.

Vücuttan nasıl atılır?

The only way to control the disease is to remove the diseased fat tissue from the body. The fats removed with the Superdry method do not reoccur if the patient follows the given programme and does not experience any hormonal problems.

Lipödemde varis tedavisi nasıl ?

Lipödemli kadınlar, kontrol grubuna göre yaklaşık 11 kat daha yüksek varis oranına sahip. Aslında çoğu zaman bir parçası. Sorun burada başlıyor, ya bu hastalar varis hastası kabul edilip varis ameliyatı yapılıyor ya da ana neden olan enflamatuvar yağı ortadan kaldırmadan varis ameliyatı oluyor.

Lipödem veya lenfo-lipödem tanısı almış 261 hastada  varis ameliyatı sonrası şişlik ve bacakta dolgunluk gibi bulgularda genelde iyileşme olmadığı veya kötüleşme görüldüğü raporlanmıştır. Bu nedenle yazarlar, varis ameliyatlarının bu hastalarda  sadece zorunlu durumlarda yapılmasını önermişlerdir.

2026 yılında yapılan bir başka çalışmada sadece varis olan hastalarla, lipödemli varisi olan hastalar karşılaştırılmış.

Lipödemi  olanlarda bu iyileşme daha sınırlı bulunmuş,

Bu bulgu, venöz girişimlerin lipödem semptomlarını doğrudan iyileştirmeyebileceğini düşündürmektedir.

Varis tedavilerinin lipödem semptomlarına olumlu etkisi sınırlıdır. Ultrason raporunda damarın geniş olması ya da kaçak olması ameliyat için yeterli değildir.

En önemli kriter reflü süresidir (≥0.5 saniye patolojik kabul edilir).

Sonuç olarak damar iltihabı (flebit), deri değişiklikleri (egzama, morumsu-kırmızı), deride yara gibi durumlarda tedavi öncelikli olur. Diğer türlü önce lipödem operasyonu, en az altı ay bekleyip damarların değerlendirlmesini tavsiye ederiz.

Lipödemde varis belirtilerini, ayırıcı tanıyı ve liposuction ile varis tedavisi farklarını gösteren bacak görseli

Lipödem ve varis arasındaki farklar: Belirtiler, ayırıcı tanı ve tedavi yaklaşımları

Are compression stockings good for varicose veins?

Compression stockings can reduce oedema but are not sufficient. We prefer to use special flat knit compression garments for treatment.

Is hot water, sauna or spa good?

No, the disease does not like the heat. Spas, saunas or sunbathing increase oedema and trigger complaints. You should also avoid thermal (heat-generating) tightening devices.

Are legs thinner with sleeve gastrectomy?

No, it is not. This fat resists stomach reduction surgeries. Even if the patient loses significant weight from the upper body, the legs remain thick and the disproportion becomes more prominent.

Does lipoedema recur after surgery?

Since we remove diseased fat tissue with the Superdry method, if you follow the lifestyle we recommend, we aim to ensure that the results are permanent and do not occur again in the same area.

Is Lipoedema Treatment Possible Without Surgery?

In the medical literature, we define it as a genetically and hormonally based fat metabolism condition. Therefore, it is not possible to completely eliminate the affected tissue with diet or sport alone.

Does Lipoedema Pass with Home Treatment?

It is not a simple regional adiposity; it is a genetically based, progressive fat tissue disorder. Home methods only reduce oedema and provide pain relief. As a result ankle and we need surgery for permanent correction of the leg form.

Lipoedema Treatment Prices 2026

Hastalarının sağlık sorunlarını, kilo ve psikolojik sorunlarını da göz önüne alana, hastalığın nüksünü önlemeye yönelik programı içine alan, deri kalitesinin geliştirilmesine yönelik rejeneratif yöntemlerin de dahil edildiği kapsamlı bir tedavidir. Fiyatlandırmayı; hastalığın evresine, bacak, kol veya basen gibi işlemin yapılacağı alan sayısına göre kişiye özel belirliyoruz.

Knee joint problems in lipoedema?

Hastaların dizlerinde X leşme, içe dönme sıktır ve eklem dışına aşırı yük biner. Diz içi yağlanma bunda önemli bir neden. Ayak tabanı kemerinde giderek çökme oluşur ve yürüyüş mekaniği değişir.

Hastalarda anabolik direnç vardır, yani kas güçlendirme daha zordur. Özellikle kuadriseps ve kalça abdüktörlerinde  muscle weakness is common. This makes the problem worse.

When misalignment chondromalacia (softening of the kneecap) progresses in the joint, synovitis (inflammation of the membrane) develops in the joint capsule.

The patient's “lipoedema knee pain” is due to both inflammation of the adipose tissue and synovitis of the joint.

Solution: Firstly, it is very important to remove the fat around the knee and intra-knee stem cell injection in the same session.

Removal of fat around the knee contributes greatly to the correct alignment of the knee and relieves knee joint functions.

Stem cells where they were given  It can produce new cartilage and stop joint inflammation and improve blood flow in the joint. It has been found to increase joint lubrication and improve joint functions.

On top of these two treatments, strengthening the right muscles is another important step.

SLIM-SHAPE-REPAIR-STRENGTHEN.

What are the Differences Between Lipoedema and Lymphedema?

Lipoedema and Lymphedema Differences

Comparison infographic showing the differences between lipoedema and lymphoedema; symmetry, foot involvement, Stemmer's sign, pain and tissue structure are compared.

For this, the flexibility of the back of the toe is checked. If it is not flexible, very hard and not stiff, this is in favour of lymphedema. Previously, it was said that lipoedema does not involve the foot. However, we can say from our experience that it can progress to the middle of the foot.

How are lipoedema and lymphoedema distinguished by examination?

WHAT ARE LIPOEDEMA STOCKINGS?

🦵CCL3 düz örgülü kompresyon çorabı, hastalıkta kullanılan yüksek basınçlı özel bir medikal çoraptır.

🦵CCL refers to the pressure level.

Plain knit socks are made with a special production technique. These socks are thicker, more durable and less flexible than other socks. Thanks to these features, they support the leg tissue better and are more effective in oedema control.

🦵Therefore in the disease plain knit compression stockings are preferred.

🦵In this disease, lymph circulation can be affected over time. Compression stockings can help improve circulation by supporting the upward transport of lymph fluid.

🦵Many patients experience pain, tenderness and a feeling of pressure in their legs. The stable support provided by plain knit socks can contribute to the reduction of these complaints.

Flat-knit socks can help the leg shape look more balanced by tightly hugging the tissue. This also limits the outward expansion of the tissue.

🦵May slow the progression of the disease

🦵Socks should generally be worn in the morning hours, before swelling in the legs. In this way, compression is more effective.

🦵Socks are mostly worn during the day and removed in the evening before going to bed. However, the duration of use may vary according to the doctor's recommendation.

🦵Flat knitted compression socks are supplied according to individual measurements.

🦵If used incorrectly, it can cause pain and numbness and skin irritation.

🦵The wrong sock does not provide adequate compression, causing the sock to slip or fold and can lead to circulatory problems

🦵The leg muscles contract and relax during walking or exercise. This condition muscle pump the so-called mechanism.

🦵Compression socks support this mechanism.

🦵Therefore, when wearing socks, the patient recommended to be mobile.

What is ankle thinning with Superdry 4D liposuction?

Lipoedema Treatment: Bloodless, No Risk of Fat Embolism, Lymph Protective Superdry 4D

Comparison of lipoedematous and post-procedure appearance with Superdry 4D liposuction method for ankle thinning

With Superdry 4D liposuction, a treatment that is bloodless, without the risk of fat embolism and reveals the Achilles image with a lymph-protective approach is possible. Ankle thinning may not be limited to the ankle. Depending on the situation, it progresses upwards or towards the back of the foot.

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Dr Karacalar's Books

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Prof. Dr. Ahmet Karacalar - Aesthetic, Plastic and Reconstructive Surgery Specialist, Istanbul